We uphold rigorous standards of excellence, aiming to develop tests that detect diseases at earlier stages and with greater accuracy. Our discoveries undergo thorough validation, consistently confirming their precision.
Data You Can Rely On
Insights from our Pan Cancer Study
In a plasma proteomics study of 18 solid tumors, we have uncovered significant sex differences in cancer detection. Recognizing these biological differences, we see the potential benefits of sex-specific biomarker panels to enhance detection accuracy.
Figure A. The volcano plots showing differential abundances of proteins among both sexes, males, and females. Top 100 proteins based on their p-value are highlighted in red.
Figure B. Ranking of the top 10 proteins based on p-value in males and females as well as the ranking of 10 randomly selected proteins in males and females.
Figure C. The scatter plot of p-values for each protein among males and females.
Figure D. The Venn diagram of top 100 proteins based on volcano plots in males
and females.
Source (Budnik et al. 2023)
Efficient Protein Set for Detection
Our results illuminate that by measuring just a set of 10-20 proteins, we can detect the presence of many cancers in their early stages, showcasing the efficiency and precision of our approach.
Cutting-Edge Detection Approach
Our plasma protein panels can accurately differentiate between cancerous and non-cancerous samples, as well as between different types of cancers.
Figure. Sensitivity of detection panel at the specificity of 99% by stage for males and females.
Our protein panels are optimized to detect cancer with exceptional accuracy in the early stages of development.
Early-Stage Precision
Figure A. ROC curve (receiver operating characteristic curve) of detection panel for males and females.
Figure B. Sensitivity of the detection panel at the specificity of 99% for each stage of the cancer for males and females.
We've expanded our research to include urine-based protein panels. Preliminary results indicate that our urine panels demonstrate remarkable accuracy, rivaling, and in some cases exceeding, the performance of existing tests.
